Effect of electroacupuncture at neiguan (PC 6) and baihui (GV 20) on CHOP and caspase-12 gene expressions in rats after ischemia-reperfusion injury

Item

Title

Effect of electroacupuncture at neiguan (PC 6) and baihui (GV 20) on CHOP and caspase-12 gene expressions in rats after ischemia-reperfusion injury

Description

J Acupunct Tuina Sci (2017), Li Wen-hui;Lin Ya-ping;Tan Xing;Song Yang.

Abstract

In traditional Chinese medicine (TCM), electroacupuncture (EA) has been regarded as an effective method in treating patients under cerebral ischemia-reperfusion injury (IRI). It was found that acupuncture can be an outside-signal to adjust genes related to apoptosis in ischemic reperfusion rats. Acupuncture can not only inhibit apoptosis-related genes but also promote protective genes after cerebral ischemic reperfusion. Neiguan (PC 6) and Baihui (GV 20) can promote the flow of qi and blood, unblock and activiate the meridians and collaterals, which is the principle acupuncture treatment for ischemic reperfusion. That is why those points were selected to discuss one of the protective mechanisms of EA in treated cerebral ischemic reperfusion. Therefore, our research is to observe the protective effects of EA through stimiulating Neiguan (PC 6) and Baihui (CV 20) points and to see whether one of the protective mechanisms of EA is related to apoptosis pathway of ERS through observing changes of CHOP and caspase-12 gene expressions in rats with cerebral ischemic reperfusion.

Alternative Title

J Acupunct Tuina Sci

Creator

Date

Date Created

12/1/2018

Language

English|Chinese

Source

Subject

Type

Journal Article

issn

1672-3597

issue

1

page end

13

page start

8

volume

15

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