Effects of eye-acupuncture on the expression of brain-derived neurotrophic factor in the brain of rats with cerebral ischemia reperfusion
Item
Title
Effects of eye-acupuncture on the expression of brain-derived neurotrophic factor in the brain of rats with cerebral ischemia reperfusion
Description
W J Acupunct Moxi (2013), Gao, Yuan;Wang, Zhe;Ma, Xian-de;Jing, Huan.
Abstract
To observe the effects of eye-acupuncture therapy and body-acupuncture therapy on the expression of brain-deprived neurotrophic factor (BDNF) in rats with cerebral ischemia reperfusion injury (CIRI). Methods: According to random number table, 48 SD rats were randomly divided into 6 groups, including normal control group (group A), sham operation group (group B), model group (group C), eye-acupuncture group (group D), non-acupoint of eye-acupuncture group (group E) and body-acupuncture group (group F), eight rats in each group. Artery infarction reperfusion model were prepared by using suture-occluded method. Liver region, upper energizer area, lower energizer area and kidney region were selected in the group D. Acupuncture was carried out at the point located at 3 mm from the acupoint areas in the group E. Quchi ( LI 11), Zusanl ( ST 36) and other acupoints were selected in the group F. Zea Longa scoring method was utilized for scoring the neural functions of rats; real-time PCR was carried out to examine the expression level of BDNF mRNA in the brain 72 h after ischemia reperfusion; western blot was carried out to examine the expression level of BDNF protein in the brain 72 h after ischemia reperfusion.
Alternative Title
W J Acupunct Moxi
Creator
Date
Date Created
6/18/2014
Language
Chinese
Subject
Type
Journal Article
doi
http://dx.doi.org/10.1016/S1003-5257(14)60006-4
issn
1003-5257
issue
4
page end
27
page start
23
volume
23