Efficacy of Wu Mei Wan for treating equine metabolic syndrome related laminitis and uveitis poorly responsive to conventional medicine
Item
Title
Efficacy of Wu Mei Wan for treating equine metabolic syndrome related laminitis and uveitis poorly responsive to conventional medicine
Description
Am J Trad Chin Vet Med (2019), Lankenau, Cynthia J.
Journal Publication
issn
1945-7693
Date
Language
English
Author(s)
Abstract
A classical Chinese herbal medicine, Wu Mei Wan, was used to treat horses affected with equine metabolic syndrome (EMS) with concurrent laminitis and/or uveitis associated with a pattern in Chinese medicine known as Jue Yin syndrome. Twenty-four EMS patients with concurrent laminitis (16/24) or uveitis (4/24) or both presentations (4/24) that were poorly responsive or unresponsive to conventional treatments were enrolled. All horses were orally medicated with Wu Mei Wan for 30 days. Horses with laminitis, received baseline scores (0-5) before treatment followed by weekly scores until study termination. Horses with uveitis were assessed by the degree of eye opening at the same time points (0 fully open to 4 tightly shut). Successful treatment outcome for either condition, was at least 50% improvement (with respect to the clinical assessment score) by the end of the 4-week study. All 20 horses with laminitis had improved lameness scores after 1 week of treatment (mean score 3.85 ±0.88 reduced to 1.2 ±1.11) with percent mean reduction among subjects of 69.8%, 81.2%, 93.8% and 97.1% after 1, 2, 3, and 4 weeks of treatment, respectively. All 8 uveitis subjects had improved scores after 1 week (mean score 3.25 ±0.89 reduced to 0.625 ±0.74) and mean reduction of 80.2%, 86.5% after 1 and 2 weeks of treatment, respectively. The response rate for both laminitis and uveitis was 100% (50% improvement, week 4) with all p-values < 0.001. Study results suggest that the Chinese herbal medicine, Wu Mei Wan, may be an effective treatment for unresponsive cases of laminitis and/
or uveitis associated Jue Yin and equine metabolic syndromes.
or uveitis associated Jue Yin and equine metabolic syndromes.
volume
14
issue
2
Abbreviated Journal Title
Am J Trad Chin Vet Med
page start
31
page end
44