Effect of acupuncture on NSE and Hcy levels and magnetic resonance spectrum in cerebral infarction patients
Item
Title
Effect of acupuncture on NSE and Hcy levels and magnetic resonance spectrum in cerebral infarction patients
Description
J Acupunct Tuina Sci (2013), Zheng, Su;Xu, Jing;Wang, Peng;Luo, Qiang
Abstract
Objective—To observe the effect of stage-based acupuncture on neuron specific enolase (NSE), homocysteine (Hcy) levels and magnetic resonance spectrum in patients with cerebral infarction. Methods—Ninety eligible subjects were randomized into two groups, 45 in each. The control group was intervened by conventional neurological medication, while the treatment group was by acupuncture according to different stages in addition to the conventional neurological medication. The therapeutic efficacy was evaluated after a treatment course. Results—The total effective rate was 97.8% in the treatment group versus 77.8% in the control group, and the treatment group was significantly superior to the control (P<0.01). In comparing the National Institutes of Health stroke scale (NIHSS) score, NSE and Hcy levels, the treatment group was lower than the control group, and the differences were statistically significant (P<0.01). The analysis of magnetic resonance spectrum revealed that the treatment group had a markedly higher N-acetyle-aspartate (NAA) concentration and lower lactic acid (Lac) concentration than the control group (P<0.01). Conclusion—Stage-based acupuncture significantly increases clinical efficacy and heals neurological function deficit, and its mechanism is possibly related to the decrease of NSE and Hcy levels, increase of NAA, and elimination of Lac.
Alternative Title
J Acupunct Tuina Sci
Date
Language
English
issn
1672-3597
issue
4
page end
217
page start
212
volume
11