Influence of electroacupuncture on tumor necrosis factor-α and vascular endothelial growth factor in rats with experimental arthritis

Item

Title

Influence of electroacupuncture on tumor necrosis factor-α and vascular endothelial growth factor in rats with experimental arthritis

Description

J Acupunct Tuina Sci (2012), Jie, Gao

Abstract

Objective: To observe the effect of electroacupuncture (EA) on tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF) in peripheral blood and joint fluid of collagen-induced arthritis (CIA) rats. Methods: After CIA rat models were successfully established, the rats were given corresponding intervention treatments. The levels of TNF-α and VEGF in peripheral blood and joint fluid were measured. Results: The levels of TNF-α and VEGF levels in peripheral blood and joint fluid of CIA rats were higher than those of normal group (P<0.05); EA treatment significantly decreased the index levels, of significant difference compared with those before treatment (P<0.05), as well as the model group (P<0.05). Conclusion: EA can significantly decrease the TNF-α and VEGF levels in peripheral blood and joint fluid of CIA rats, and helps restrain further development of the disease.

Alternative Title

J Acupunct Tuina Sci

Creator

Date

Language

English

Source

Subject

issn

1672-3597

issue

4

page end

208

page start

204

volume

10

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