Electroacupuncture may support orthobiologic therapeutic outcomes for knee osteoarthritis: a systematic review
Item
Title
Electroacupuncture may support orthobiologic therapeutic outcomes for knee osteoarthritis: a systematic review
Description
JASA (2020), Johnson, Amber L.
Abstract
Objective: Osteoarthritis is a degenerative joint disease that affects nearly 27 million people in the United States, with the most common joints reported being hips, knees, and hands. A clinical diagnosis for osteoarthritis is pain, stiffness, and loss of function upon physical examination. Nearly nineteen percent of the American population over the age of forty-five have knee osteoarthritis, and this figure is expected to increase amid an aging population. The field of Cell Therapy emphasizes the physiological process of stimulating the repair of living tissue that was once believed to be irreparable by the body. Conventional therapies that treat osteoarthritis focus on reducing pain and improving function. Electroacupucture has demonstrated immune modulation. This paper evaluates current literature to determine whether the immune response to electroacupuncture is complementary to cell therapy in the treatment of knee osteoarthritis, thereby creating a sub-discipline of Traditional Chinese Medicine within the field of Cell Therapy using Orthobiologics.
Methods: Search methods utilized PubMed, Google Scholar, and EBSCO host databases. Articles searched included years 2000 through 2018.
Results: Biochemical precursors to dopamine and acetylcholine, and cell signaling pathways within the extracellular environment, inhibit pro-inflammatory cytokine production. Standardization of protocols concerning the harvesting and processing of cell-based, orthobiologic products is strongly recommended by researchers to provide consistency among therapeutic outcomes.
Discussion: This systematic review represents a translational study of the immune modulatory effects of electroacupuncture as related to the use of cell therapy.
Conclusion:
Evidence-based practices utilizing electroacupuncture to stimulate the vagus nerve demonstrates immune modulation. More research is needed to investigate the complementary effect of electroacupuncture to strengthen the clinical outcomes in the process of cell therapy using orthobiologics for the treatment of knee osteoarthritis.
Methods: Search methods utilized PubMed, Google Scholar, and EBSCO host databases. Articles searched included years 2000 through 2018.
Results: Biochemical precursors to dopamine and acetylcholine, and cell signaling pathways within the extracellular environment, inhibit pro-inflammatory cytokine production. Standardization of protocols concerning the harvesting and processing of cell-based, orthobiologic products is strongly recommended by researchers to provide consistency among therapeutic outcomes.
Discussion: This systematic review represents a translational study of the immune modulatory effects of electroacupuncture as related to the use of cell therapy.
Conclusion:
Evidence-based practices utilizing electroacupuncture to stimulate the vagus nerve demonstrates immune modulation. More research is needed to investigate the complementary effect of electroacupuncture to strengthen the clinical outcomes in the process of cell therapy using orthobiologics for the treatment of knee osteoarthritis.
Alternative Title
JASA
Creator
Date
Language
English
Subject
issn
2377-3723
issue
1
page end
27
page start
18
volume
7